I would go as far to say that you have never heard of this hormone before, however i would go even further to say, that after reading this article, you will never forget it?
Peptide YY – sounds like some sort of alien doesnt it?
Peptide YY, also known as peptide tyrosine tyrosine, but for todays sake and for the longevity of my fingers whilst typing, we will call it PYY.
Lets lay the foundations here for a minute.
Im sure i am speaking to the converted here, but please stay with me, it is very important.
At the moment obesity is one of the biggest challenges that this world faces, we don’t need to be a rocket scientist to figure that one out huh?
Anyhow obesity and PYY have a pretty close relationship, let me explain:
Recent studies have improved our understanding of energy homeostasis by identifying sophisticated neurohumoral networks which send signals between the brain and gut in order to control food intake.
So what that means is that our Brain and Gut communicate together to tell us if we are hungry or not, simple huh? well This is where PYY comes into play.
PYY is an appetite suppressing hormone, which is isolated originally from the upper small intestine, PYY is released from the L cells of the distal gut in response to any ingested nutrients along with two other gut hormones. To keep you from losing focus i wont introduce these hormones, lets just call them, 2 & 3.
The way in which PYY is secreted, has suggests that this hormone can play a pivotal role in satiety.
Circulating PYY concentrations are low in the fasted state and they increase rapidly following a meal, with a peak at 1-2 hours and can remain elevated for several hours.
A new review in Experimental Diabetes Research suggests that PYY may have a role in the pathogenesis of a number of anorectic conditions such as inflammatory bowel disease, steatorrhea, tropical sprue, and cardiac cachexia, since plasma PYY levels are elevated in patients with these conditions.
This review also showed that the administration of PYY shows a reduction in food intake and body weight gain in rats.
In both lean and obese human subjects, intravenous administration of PYY reduces appetite and food intake with observed plasma PYY levels similar to the physiological levels after a meal; once again this data suggests that the physiological effect of PYY is to suppress food intake.
Furthermore, PYY has been reported to regulate energy expenditure, delay gastric emptying, reduce acid secretion, and inhibit gallbladder contraction and pancreatic exocrine secretions.
Also we need to note that Circulating PYY levels are low in obese subjects, OH NO, so it can make it even harder to shift that stubborn body fat if you are already obese?.
Leptin also reduces appetite in the response to feeding, however the pit fall for obsess people is that they develop a resistance to leptin. (what, that is contradictive), yes it is, but there is an explanation, but we will save that one for another day.
On the other hand, attempts to use PYY directly as a weight-loss drug have met with some success.
In the The New England Journal of Medicine, Researchers noted that caloric intake during a buffet lunch offered two hours after the infusion of PYY was decreased by 30 percent in obese subjects –
WAIT A MINUTE, before you jump on google and try and find out when you can order the next shipment of PYY, (which i highly DO NOT recommend) there is more to it, but better yet, we can suggest some strategies so you can Increase PYY normally. YAY, its all ok again.
Increased production of PYY can be prompted by the following:
Various eating patterns, food choice and supplements can greatly impact the production of this hormone and thereby help regulate your appetite.
In 2006 the US National Library of Medicine, tested human subjects on the relationship between a high-protein intake vs a low protein intake, results showed that the Increased Protein consumption, induced the greatest release of the anorectic hormone peptide YY (PYY) and the most pronounced satiety.
Dr. Rachel Batterham, suggests that, while simple diet changes could be as simple as a 2 to 3 percent increases in protein and smaller reductions in starchy carbohydrates, we still need to remember that it is a long term change, not a unattainable diet, such as the one that rhymes with Fatkins.
So summing it all up.
If you are still under the impression that to much protein will turn me into the incredible hulk, then you are mistaken, (of course there is a limit to your daily protein intake, however this will vary from individual to individual.
A study by the Nutrition Journal, 9: 72 showed that there were no detrimental effects on kidney, liver or bone health after one year of consuming protein intakes of 2.2g/kg of lean body mass.
Another study showed that a diet consisting of 25% protein with an additional 50g of supplemental protein daily, had no ill effects on health (it also happened to be the best for maintaining a healthy weight after dieting.
Be sure to be getting the majority of your protein intake from quality whole foods, such as:
However in this fast paced day and age, we need the good old back up plan, and this is where a great quality protein supplement comes in handy.
Now with all the confusion and all the expensive marketing, when it comes to what protein is best to purchase, it can become very overwhelming, trust me, i answer this questions many times a day.
Here is how to pick a good protein:
Pick a protein that has a high % around 80% is best, many companies out there just fill the proteins with low grade quality so they can keep stocking the shelves, and it is the end consumer who end up missing out.
Also be sure your protein supplement is low in sugars, trust me, you can find some great tasting proteins out there that are still great quality.
Don’t be fooled by the 500gm containers they have in the supermarkets and chemists, the mark up on those things are unbelievable, dont get me started.
That’s why we have created Fiit CHICK SUPPLEMENTS, head on over and check out what we have to offer, as you will see it is only quality goods at unbelievable prices.
Seriously one of our products sells for $49.95 for 25ogm, one of the major supplement brand sells the exact same thing for $49.95 for only 50gm, i rest my case.
So check out the latest fit chick supplement range here, especially our Best Seller, Thermo Curves, it has extra ingredients that also help with fat burning.
Section of Investigative Medicine, Imperial College London, Commonwealth Building, Du Cane Road, London W12 0NN, UK
Li, Z., Treyzon, L., Chen, S., Yan, E., Thames, G., & Carpenter, C. L. (2010). Protein-enriched meal replacements do not adversely affect liver, kidney or bone density: an outpatient randomized controlled trial.
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